Carsinoma Doctor

Posts Tagged ‘Women’

One type of echovirus (EV1) could be an effective agent against ovarian cancer, according to International Journal of Cancer.

Researchers at the University of Newcastle, New South Wales, Australia, conducted an experiment in animal model indicates that the EV1 is capable of destroying tumor cells of ovarian cancer, opening certain therapeutic possibilities.

Scientists found that EV1 infects and destroys the cells of human ovarian cancer, without damaging the surface of normal cells of the ovary.

Ovarian tumors grafted into mice and inoculated directly EV1 in these tumors. Very quickly, it reduced the size of them and even other tumors distant from the site of injection.

Also abdominal administration of EV1 was effective against the proliferation of ovarian cancers grafted into the abdominal cavity of mice.

The researchers suggest that, given these data on ovarian cancer, presents an attractive therapeutic alternative to treatments involving surgery followed by chemotherapy.

According to a report on the health of European women, there is considerable discrepancy between different European countries both in patterns of incidence and mortality due to lung cancer in relation to the smoking habits of 20 to 30 years earlier. Thus, the highest mortality trends of the European Union are located in the Netherlands, Poland, Norway, Sweden and Britain. However, smoking among women is now more prevalent in southern Europe than in the north, which makes predicting an increase in mortality in Southern European countries, among which is Spain.

Also according to the report, smoking is a preventable cause of illness and death most important in Europe. The prevalence of women smokers for the period 1996-2003 ranged from 6.8% in Portugal and 32% in Austria but recent reports suggest that is increasing and is around 20% in most European countries. “In Spain, the president of SEOM highlights for the period 2002-2005, the prevalence in women was higher than 20% and most troubling, 30% in adolescents.”

Following the steady increase in the number of women diagnosed with lung cancer attending oncology consultations in recent years in Spain, in 2007 it launched a project sponsored by the Spanish Society for Medical Oncology (SEOM) and led by Drs Pilar Garrido, Dolores Isla, Enriqueta Felip and Nuria Viñolas, as oncologist lung cancer.

The project, called World 07, is a database of prospective, multicenter epidemiological and developed to collect demographic data, habits, clinical features and treatment of women diagnosed with lung cancer in 36 hospitals in Spain. The objective is to analyze a total of 2,000 patients to evaluate differences between sexes, having included from October 2007 until now over 500 patients.

The majority had adenocarcinoma histology (74%), 43% nonsmokers, 42% with a family history of cancer (one third of lung cancer), with a median survival for advanced NSCLC 17 months, confirming the better prognosis women already known from other series. A better understanding of gender differences may contribute to the administration of a therapeutic strategy that is more effective.

Experts warn that this tumor, associated with smoking appears increasingly younger ages.

Lung cancer has reversed its trend and in recent years, the incidence is increasing in women, while decreasing the cases in men. The main cause of this cancer is the snuff, to which women are most susceptible. The characteristics of this tumor are different in women and men, although smoking has the same negative influence in both sexes, studies indicate that exposure to snuff as well, women are more likely to develop lung cancer.

SEOM President, Dr. Emilio Alba, noted that “in Spain are seeing changes in the incidence of this cancer, with a decrease in men and women increased their presentation at younger ages, a trend that will continue in coming years, especially in relation to the habit of smoking. ”

Given this gender health problem, the Spanish Society for Medical Oncology (SEOM), the Ministry of Health and Social Policy and the National Committee for Smoking Prevention (CNPT), have joined forces to call for social awareness, coinciding with the recent celebration of World No Snuff, which this year has focused on women.

“Currently women are not aware of the risk of lung cancer who have” continued Dr. Alba. According to recent studies, women have a higher susceptibility to snuff, which means that the risk is higher with less time or quantity of snuff smoked, compared with men. ”

According to SEOM, about 20,000 are diagnosed with lung cancer each year in Spain, which represents 12% of all cancers and 18.4% of tumors among men (18,000 cases) and 3.2 % among women (2,000 cases). That is, 68 new cases occur annually in men and 14 new cases per 100,000 inhabitants. In addition, according to the INE, in 2006 (latest year recorded) 19 703 people died in Spain from the disease.

Endometrial carcinoma is the fourth leading cause of cancer in women after breast, lung and colon, in developed countries. Because it seemed important to evaluate the effectiveness of a noninvasive method, such as transvaginal ultrasound in screening women with risk factors for developing this disease, even more so taking into account the great curability of the same (the curable of the 10 most common cancers) if it is diagnosed and treated early.

Most women with endometrial carcinoma are postmenopausal and present consultation vaginal bleeding, with invasive methods such as biopsy and curettage, the most widely used for exploration. In these cases where we want to assess whether these methods can be replaced by transvaginal ultrasound, taking into account its complications.

We also want to deepen on the use of this diagnostic imaging in patients treated with tamoxifen for having had breast cancer and those with hormone replacement therapy.